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A Knowledge Environment for the Bone Field

NOTE FROM THE EDITOR

HAPPY NEW YEAR!!!

On behalf of IBMS BoneKEy, I wish to thank you, our readers, for your support of BoneKEy in 2009. Thanks to your loyalty to BoneKEy, more than 22,000 readers visited BoneKEy in 2009, an excellent showing for our online Knowledge Environment. In addition, I thank our many authors and peer reviewers in 2009, whose efforts and expertise help ensure the high quality of content you can always expect to find on BoneKEy. I look forward to continued success in 2010 -- be on the lookout for new features and initiatives throughout the year -- and I wish all of you a very happy and healthy New Year.
--Serge Ferrari, IBMS BoneKEy Editor-in-Chief

PERSPECTIVES
Myostatin

Myostatin (GDF-8) as a Therapeutic Target for the Prevention of Osteoporotic Fractures

By Mark W. Hamrick

What role might agents that target myostatin have in future osteoporosis therapies? Dr. Hamrick discusses the in vitro and in vivo work leading to the clinical development of myostatin inhibitors as novel therapeutic agents for the prevention of bone fractures.

Fibrous Dysplasia of Bone and McCune-Albright Syndrome

By Roland D. Chapurlat

In his review, Dr. Chapurlat reviews the role of the GNAS mutation; detection of mutated bone cells; and various therapies, including the use of bisphosphonates.


EDUCATIONAL RESOURCES

View BoneKEy's Introduction to Clinical Osteoporosis Teaching Slide Set

COMMENTARIES

Is the Genomics Glass Half Empty or Almost Completely Empty?

By John A. Eisman

A recent Annals of Internal Medicine meta-analysis from Richards et al. of candidate genes in association with osteoporosis and osteoporotic fracture offered some disappointing results; Dr. Eisman discusses the implications of the study for the future of osteoporosis genomics.


MEETING REPORTS

From the IX International Meeting on Cancer Induced Bone Disease:

Biology and Treatment of Prostate Cancer Bone Metastasis

By John M. Chirgwin


Cancer-Associated Fibroblasts

Claire M. Edwards


Hematopoietic Stem Cells, Cancer Stem Cells, and the Hematopoietic Stem Cell Niche

By Elisabeth A. Pedersen, Yusuke Shiozawa and Russell S. Taichman


Imaging and Proteomics of Bone Metastasis

By Serk In Park and Laurie K. McCauley


Tumor-Associated Osteoclastogenesis and Angiogenesis

By Toshio Matsumoto and Masahiro Abe


Coming Soon: The program and abstracts from the CIBD meeting will soon be appearing in Bone. Stay tuned...


DID YOU MISS?
Advances in Therapeutics: Meeting Report from the 31st Annual Meeting of the ASBMR


MEETING SUPPLEMENTS

IBMS Sun Valley Workshop: Musculoskeletal Biology


1st Advances in Rare Bone Diseases Scientific Conference


UPCOMING EVENT

March 14-19, 2010

IBMS Davos Workshops 2010

IBMS BoneKEy is published by the International Bone & Mineral Society which is solely responsible for the content of the site. IBMS accepts support from corporate sponsors in the form of unrestricted educational grants, however, the content of the site is not reviewed or influenced by corporate sponsors in any way. All editorial decisions are the sole responsibility of the IBMS BoneKEy editorial board and all original material is peer-reviewed.

Copyright © 2010 by the International Bone & Mineral Society
BoneKEy Editorial Board | International Bone & Mineral Society

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