Collections
NEWS - Timely articles written from a journalistic perspective on hot areas in the bone field.
From Video Games to Bisphosphonates?
Neil A. Andrews
During The Management of Bone Fragility/Low Bone Mass in Children and Adolescents, the eighth IBMS BoneKEy Webinar, an international panel of experts expressed concern that the lifestyle adopted by the current generation of youngsters may have serious skeletal consequences.
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PERSPECTIVES - Insightful, thematic reviews of key topics on both the basic science and clinical sides.
Bone Sarcomas: Pathogenesis and New Therapeutic Approaches
Dominique Heymann and Françoise Rédini
The authors discuss the histological and molecular diversity of bone sarcomas, as well as pathogenesis, animal models, and new therapeutic approaches for these tumor types.
[Abstract] [Full Text] [PDF]
COMMENTARIES - Analyses of specific pathbreaking papers appearing in all of the major scientific and medical journals.
Inhibition of Osteoclast Differentiation by the Interleukin (IL)-1 Family Cytokine IL-33
Gaby Palmer
The author analyzes two recent papers by Schulze et al. in JBMR and Zaiss et al. in J Immunol. providing the first in vivo data indicating a role for IL-33 in the inhibition of osteoclast differentiation.
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MEETING REPORTS - Comprehensive examinations of new findings presented at the major bone meetings.
The Study of Skeletal Aging Is Coming of Age: A Forum on Aging and Skeletal Health
Stavros C. Manolagas and Robert L. Jilka
The authors provide a comprehensive overview of a forum, organized by ASBMR and the National Institutes of Aging, Child Health and Human Development, and Arthritis and Musculoskeletal Skin Diseases, that covered emerging concepts on the epidemiology, underlying mechanisms, and therapeutic management of age-related bone loss and fractures.
[Full Text] [PDF]
NOT TO BE MISSED - Annotations, written by the IBMS BoneKEy editors, on the most important articles published in the literature each month.
Okamoto et al. Conditional deletion of Bmpr1a in differentiated osteoclasts increases osteoblastic bone formation, increasing volume of remodeling bone in mice. J Bone Miner Res. 2011 Jul 22. [Epub ahead of print]
In order to clarify the function of BMP signals in osteoclasts during bone remodeling, the authors deleted BMP receptor type IA (BMPR1A) specifically in...
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ARTICLES - Unique content covering special topics, such as new clinical guidelines.
The Epidemiology of Osteoporosis in Asia
Edith M. Lau
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ELECTRONIC LETTERS TO THE EDITOR - Comments submitted by readers in response to original content published on BoneKEy.
All Clinicians Are Bayesians
Robert S. Fredericks
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