Collections
NEWS - Timely articles written from a journalistic perspective on hot areas in the bone field.
The Future of Vertebroplasty: Are Randomized Controlled Trials, or Clinical Experience, the More Appropriate Guide?
Neil A. Andrews
Do results from 2 randomized trials trump more than a decade's worth of clinical experience?
[Full Text] [PDF]
PERSPECTIVES - Insightful, thematic reviews of key topics on both the basic science and clinical sides.
Skeletal Abnormalities in Anorexia Nervosa
Elka Jacobson-Dickman and Madhusmita Misra
In their comprehensive review of anorexia nervosa and bone, the authors cover hormonal determinants of adverse skeletal outcomes, effects on BMD and bone microarchitecture, and effects on adult stature.
[Abstract] [Full Text] [PDF]
COMMENTARIES - Analyses of specific pathbreaking papers appearing in all of the major scientific and medical journals.
Teriparatide: Variations on the Theme of a 2-Year Therapeutic Course
Natalie E. Cusano and John P. Bilezikian
Considering that most patients who will be treated with teriparatide or PTH(1-84) have previously received an antiresorptive drug, what is preferable: to add the osteoanabolic agent to the antiresorptive one or to switch from the antiresorptive drug to the osteoanabolic agent alone? The authors analyze two recent J Clin Endocrinol Metab. studies, one by Cosman et al. and the other by Finkelstein et al., as they attempt to answer this important clinical question.
[Full Text] [PDF]
MEETING REPORTS - Comprehensive examinations of new findings presented at the major bone meetings.
Meeting Report from the IX International Meeting on Cancer Induced Bone Disease
Various Authors
This report includes coverage of the biology and treatment of prostate cancer bone metastasis; cancer-associated fibroblasts; hematopoietic stem cells, cancer stem cells, and the hematopoietic stem cell niche; imaging and proteomics of bone metastasis; and tumor-associated osteoclastogenesis and angiogenesis
[Full Text] [PDF]
NOT TO BE MISSED - Annotations, written by the IBMS BoneKEy editors, on the most important articles published in the literature each month.
Yadav et al. Pharmacological inhibition of gut-derived serotonin synthesis is a potential bone anabolic treatment for osteoporosis. Nat Med. 2010 Feb 7. [Epub ahead of print]
This is an unusual yet remarkable paper from Dr. Karsenty's group. Unusual because it does not use a genetic approach, but a bona fide pharmacological approach to test ...
[Full Text] [PDF]
ARTICLES - Unique content covering special topics, such as new clinical guidelines.
The Epidemiology of Osteoporosis in Asia
Edith M. Lau
[Full Text] [PDF]
ELECTRONIC LETTERS TO THE EDITOR - Comments submitted by readers in response to original content published on BoneKEy.
All Clinicians Are Bayesians
Robert S. Fredericks
[Full Text]
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